Keywords:
coenzyme Q10
apoptosis
mitochondria
mechanism of action
breast cancer

  • Abstract

    Coenzyme Q10 (CoQ10) was identified in the late 1950s, and its potential role in cancer therapy appeared in the early 1960s when decreasing CoQ10 levels were found in some cancer patients. Breast cancer is a serious global health issue, and novel treatments are being developed. Its treatment is being investigated. CoQ10 has shown immune-boosting effects in clinical studies, encouraging researchers to look into its possible influence on breast cancer. Several research have looked at the link between CoQ10 and breast Coenzyme Q10 (CoQ10) was identified in the late 1950s, and its potential role in cancer therapy appeared in the early 1960s when decreasing CoQ10 levels were found in some cancer patients. Breast cancer is a serious global health issue, and novel treatments are being developed. Its treatment is being investigated. CoQ10 has shown immune-boosting effects in clinical studies, encouraging researchers to look into its possible influence on breast cancer. Several research have looked at the link between CoQ10 and breast cancer, focusing on its biological effects such as cytochrome c release and subsequent radical production. CoQ10 supplementation is commonly used by cancer patients to alleviate a perceived CoQ10 deficit associated with treatment-related toxicity. Notably, evidence shows that CoQ10 may be connected to lower tocopherol levels increasing the risk of breast cancer. However, bigger sample sizes, longer follow-up periods, and a better knowledge of the physiological role of circulating CoQ10 are required for a thorough assessment of CoQ10's possible role in breast cancer etiology. Antibacterial medications, therapy-induced adverse effects, and oxidative stress all have an impact on chemotherapy-related problems. Although CoQ10 has shown potential as an alternative breast cancer treatment, it is crucial to highlight that existing standard therapies, such as chemotherapy, radiation therapy, and hormone therapy, are not without their limitations. and targeted therapies are all options. Remain the cornerstone of breast cancer care. Always seek the most current and trustworthy information about breast cancer therapy from medical specialists.

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How to cite

Shende, P. V., Mude, G. S., & Amipara, A. G. (2024). Breast cancer treatment with coenzyme Q10 (CoQ10). Multidisciplinary Reviews, 7(11), 2024261. https://doi.org/10.31893/multirev.2024261
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